# `search_sequence` Similarity search by raw RNA sequence. Submits the sequence to the RNAcentral sequence-search service, polls for completion, and returns the top hits across the member databases. Use this when you have a nucleotide sequence and want to know what it matches in RNAcentral. If you already have an accession or a name, use {doc}`query_rnacentral`. ## Arguments | Name | Type | Required | Description | | --- | --- | --- | --- | | `sequence` | `str` | yes | The RNA (or DNA) sequence to search. Case-insensitive; whitespace is ignored. | | `databases` | `list[str]` | no | Restrict the search to specific member databases. Defaults to all. | ## Returns A markdown summary of the hits: accession, description, organism, E-value/identity, and the source database. ## Notes - The upstream service is asynchronous — the tool submits a job and polls until results are ready or a timeout is hit. Expect a few seconds of latency on a cold cache. - Very long sequences or highly repetitive sequences may be rejected by the upstream service; the tool surfaces the error message verbatim.